La biotecnología de edición genética pone a disposición de la humanidad la posibilidad de intervenir en la línea germinal. Este trabajo indaga sobre los fines de la intervención, los compromisos y la responsabilidad en su aplicación. Complementaria a la tarea ética precede la jurídica, como expresión de los valores sociales y, por ende, resulta necesaria una revisión teórica sobre las normativas internacionales, comunitarias y nacionales. Por último, se examina la magnitud del potencial efecto que puede tener en la humanidad, en (...) su dimensión colectiva, pero sin olvidar la dimensión individual, es decir, los sujetos directamente afectados en la intervención. (shrink)

The lockdown resulting from coronavirus disease 2019 has had a huge impact on peoples’ health. In sport specifically, athletes have had to deal with frustration of their objectives and changes in their usual training routines. The challenging and disruptive situation could hold implications for their well-being. This study examined the effect of the COVID-19 lockdown on changes in athletes’ reported eudaimonic well-being and goal motives over time. The relationship of resilience to changes in subjective vitality was also determined, and changes (...) in athletes’ goal motives were examined as potential mediators. Participants were 127 Spanish university athletes aged between 18 and 34 years. Approximately 4 months before the start of the lockdown in Spain, athletes responded to a questionnaire assessing their resilience, goal motives, and subjective vitality. Around 6 months later into the lockdown period, athletes’ goal motives and subjective vitality were assessed again. Growth modeling using hierarchical linear models revealed a significant decrease of autonomous goal motives and subjective vitality during the lockdown, but athletes did not show change over time in controlled goal motives. Path analysis, adjusting T2 measures for their corresponding T1 measures, showed that resilience significantly predicted changes in athletes’ autonomous goal motives, which then accounted for changes in subjective vitality. The indirect effect was significant. Resilience did not predict changes in athletes’ controlled goal motives. However, changes in controlled goal motives negatively predicted changes in subjective vitality during lockdown. The findings suggest negative impacts of the COVID-19 lockdown on athletes’ goal motives and eudaimonic well-being. Results also support the hypothesized mediational role of autonomous goal motives in the relationship between resilience and subjective vitality during the lockdown. As such, findings confirm the relevance of resilience to a key feature of athletes’ eudaimonic well-being and the importance of enhancing their autonomous goal striving. (shrink)

Este trabajo demuestra la presencia e influencia del canon literario en la enseñanza del Francés como Lengua Extranjera (FLE), condicionando las obras literarias en los manuales españoles para tal fin. Para ello, hemos seguido un itinerario que parte del análisis teórico del canon literario y de la inclusión de lo cultural en FLE para, a continuación, mostrar cómo este ha sido determinante en la enseñanza civilizacional. Todo ello se sustenta a través del estudio concreto de la literatura en torno a (...) la cultura vitivinícola. La conclusión es que, a través de este ejemplo, constatamos cómo se funden canon literario y literatura para el aula de FLE. (shrink)

Jean Jacques Rousseau definía como "segundo parto" a la transición que supone la adolescencia, al nacimiento de la nueva identidad tras la crisis. La adolescencia coge siempre desprevenido, comienza y con ella llega un tsunami de cambios y transiciones de cuerpo y mente. Por un lado la imaginación se desborda, la sensibilidad está a flor de piel, se vive con grandes dosis de vitalidad y alegría y con la certeza de que todo es posible; hasta cambiar el mundo. Sin embargo (...) se reconoce también al adolescente por los desarreglos emotivos a los que están expuestos, los sentimientos de angustia, los miedos exagerados al ridículo, la crisis de identidad y la fuerte falta de confianza en sí mismos. (shrink)

An intelligent model of the incremental capacity curve of an automotive lithium-ferrophosphate battery is presented. The relative heights of the two major peaks of the IC curve can be acquired from high-current discharges, thus enabling the state of health estimation of the battery while the vehicle is being operated and in certain cases, aging mechanisms can be suggested. Our model has been validated using a large dataset representing different degradation scenarios, obtained from a recently available open-source database.

The business world is facing a very complicated situation due to the COVID-19 pandemic. Small- and medium-sized companies —both in Spain and at the global level—are seeing their survival jeopardized by a fall in revenues. This scenario is aggravated in the case of micro-SMEs headed by female entrepreneurs. Accordingly, micro-SMEs, particularly those led by female entrepreneurs, need to reinvent themselves to overcome the current adversities that could lead to the destruction of their businesses and hence their jobs. One of the (...) ways to do this is to take advantage of digital transformation. Therefore, the aim of this paper is to analyze which variables influence the financial results of female-led Spanish micro-SMEs when they carry out social marketing actions. For that purpose, an online survey was designed and analyzed using the “PROCESS” macro. Results show that social media marketing actions have significant effects on financial performance. (shrink)

This paper addresses a variant of the job shop scheduling problem with total tardiness minimization where task durations and due dates are uncertain. This uncertainty is modelled with intervals. Different ranking methods for intervals are considered and embedded into a genetic algorithm. A new robustness measure is proposed to compare the different ranking methods and assess their capacity to predict ‘expected delays’ of jobs. Experimental results show that dealing with uncertainty during the optimization process yields more robust solutions. A sensitivity (...) analysis also shows that the robustness of the solutions given by the solving method increases when the uncertainty grows. (shrink)

In the last decades the concept of objectivity has been criticized by the "new epistemologies". These criticisms favour the consolidation of relativist and subjective positions, which condition the objectivity of scientific knowledge to such an extent that it seems to be a goal impossible to achieve.

RESUMEN La medicina tradicional herbolaria desde su evolución hasta la contemporaneidad ha sido objeto de uso para la medicina convencional. Por eso el objetivo del trabajo es describir el comportamiento de la medicina tradicional herbolaria en los sistemas de salud convencionales. Se realizó la búsqueda y análisis documental de numerosas fuentes sobre la temática pertenecientes a las bases de datos SciELO Cuba, SciELO Regional, Science Direct, Clinical Key, Cumed, Lilacslo. Se concluye que la actualidad social registra manifestaciones alentadoras en el (...) campo de la aceptación de la herbolaria como medicina complementaria por el equipo de salud y un renovado interés en el ámbito mundial por estudiar los efectos que tienen las plantas sobre la salud. ABSTRACT The traditional herbalist medicine from its evolution to the contemporaneity has been an object use for the conventional medicine. That's why the objective of the work is to describe the behavior of the traditional herbalist medicine in the conventional health systems. A search and documentary analysis of numerous sources on the subject-matter belonging to the databases SciELO Cuba, SciELO Regional, Science Direct, Clinical Key, Cumed, Lilacslo was carried out. It is concluded that the social actuality registers encouraging declarations in the field of the acceptance of the herbalist as complementary medicine for the team of health and a renewed interest in the world ambience to study the effects that have the plants on the health. (shrink)

"Guzmancismo" was a bet to provide Venezuela with modernizing politics structures controlled by the balance of interests emong the different groups of pressure. It linked the regional leaders to the centralist proyect. allowing them to have plots of power and "clientelismo" under the condition of standing surety for the public order in their states. This long historical period of Venezuela is presided by the deep impact of positivism between the venezolan elites whe searched for the conformation of their national identity.

Achieving a comfortable thermal situation within buildings with an efficient use of energy remains still an open challenge for most buildings. In this regard, IoT (Internet of Things) and KDD (Knowledge Discovery in Databases) processes may be combined to address these problems, even though data analysts may feel overwhelmed by heterogeneity and volume of the data to be considered. Data analysts could benefit from an application assistant that supports them throughout the KDD process and aids them to discover which are (...) the relevant variables for the matter at hand, or informing about relationships among relevant data. In this article, the EEPSA (Energy Efficiency Prediction Semantic Assistant) ontology which supports such an assistant is presented. The ontology is developed on the basis that a proper axiomatization shapes the set of admitted models better, and therefore, establishes the ground for a better interoperability. On the contrary, underspecification facilitates the admission of non-isomorphic models to represent the same state which hampers interoperability. This ontology is developed on top of three ODPs (Ontology Design Patterns) which include proper axioms in order to improve precedent proposals to represent features of interest and their respective qualities, as well as observations and actuations, the sensors and actuators that generate them, and the procedures used. Moreover, the ontology introduces six domain ontology modules integrated with the ODPs in such a manner that a methodical customization is facilitated. (shrink)

Substance addiction has been historically conceived and widely researched as a brain disease. There have been ample criticisms of brain-centred approaches to addiction, and this paper aims to align with one such criticism by applying insights from phenomenology of psychiatry. More precisely, this work will apply Merleau-Ponty’s insightful distinction between the biological and lived body. In this light, the disease model emerges as an incomplete account of substance addiction because it captures only its biological aspects. When considering addiction as a (...) brain disorder, it will be shown that research fails to account for the contextual, functional, and emotional aspects inherent to subjective health. It is concluded that, while the disease model is fundamental to our understanding of what happens in the brain, its brain-centred approach is cure-oriented. Instead, we suggest a care-orientated approach, which understands and treats the psychological feel as bodily experience situated in an environment, allowing for a more encompassing therapeutic perspective. (shrink)

We study possible Scott sentence complexities of linear orderings using two approaches. First, we investigate the effect of the Friedman–Stanley embedding on Scott sentence complexity and show that it only preserves $\Pi ^{\mathrm {in}}_{\alpha }$ complexities. We then take a more direct approach and exhibit linear orderings of all Scott sentence complexities except $\Sigma ^{\mathrm {in}}_{3}$ and $\Sigma ^{\mathrm {in}}_{\lambda +1}$ for $\lambda $ a limit ordinal. We show that the former cannot be the Scott sentence complexity of a linear (...) ordering. In the process we develop new techniques which appear to be helpful to calculate the Scott sentence complexities of structures. (shrink)

La traducción que al inglés hace el ilustre profesor norteamericano Harold Raley (cuya filosofía sigue a Ortega y a Marías) resulta excelente. El profesor Harold Cecil RALEY nació el año 1934 en el Estado de Alabama (USA), en cuya Universidad se doctoró en Lenguas y Literaturas Románicas, y quiso especializarse en la obra de José Ortega y Gasset. Casado y padre de varios hijos, ha sido catedrático de Lengua y Literatura españolas de la Universidad del Estado de Oklahoma desde 1964; (...) también catedrático y decano de Bellas Artes y Humanidades en la Houston Baptist University (nombrado por ella Distinguished Professor). Entre otros libros, es autor de los siguientes: "Ortega y Gasset, filósofo de la unidad europea" (Prólogo de Julián Marías. Revista de Occidente. Madrid, 1977; edición inglesa: "José Ortega y Gasset, the Philosopher of European Unity". The University of Alabama Press. USA, 1971); "La visión responsable. La filosofía de Julián Marías" (Prólogo de José Luis Pinillos. Espasa-Calpe. Madrid, 1977; edición inglesa: "Responsible Vision: The Philosophy of Julián Marías". The American Hispanist. Clear Creek, Indiana. USA, 1980); "Julián Marías. Una filosofía desde dentro" (Alianza Editorial. Madrid, 1997; edición inglesa: "A Watch over Mortality: the Philosophical Story of Julián Marías". The State University of New York Press. USA, 1997); "El espíritu de España" (Prólogo de Julián Marías. Alianza Editorial. Madrid, 2003; edición inglesa: "The Spirit of Spain". Halcyon Press. Houston. USA, 2002); "The Light of Eden. A Christian Worldview" (John M. Hardy Publishing. Houston. USA, 2008); "Language Oddities. Quirks and Curiosities of English and Other Languages" (Kingsle. Houston. USA, 2011); "Louisiana Rogue. The Life and Times of Pierre Prospère-Tourmoulin translated by Peter Tourmoulin" (Lamar University Press. Beaumont. USA, 2013); "The Unknown God: Mysteries of Deity, Time, Space, and Creation" (Charleston, SC, USA, 2011. También es autor de más de un centenar de estudios y artículos sobre temas filosóficos y literarios. Además ha traducido al inglés algunos de los libros de Julián Marías. (shrink)

Kant controversially opposed political revolutions; yet, in morality, he clearly encouraged a revolutionary attitude. Drawing especially on the relevant texts in the Metaphysics of Morals, the Religion, the Education and the Anthropology, I explore the conceptual underpinnings of Kant’s position, arguing that Kant’s contrast between moral revolution and reform is at the basis of his twofold notion of noumenal and phenomenal virtue, which in turn explains the contrast he draws between principled versus imitative behaviour in the Education. On this basis, (...) I defend the complementary role of political reform and moral revolution in his approach to cultural progress. (shrink)

En el trabajo se propone difundir la teoría y los enfoques referidos a la ciencia de la sostenibilidad, con especial énfasis en el contexto académico cubano, al relacionar su emergencia a las urgencias que surgen en los vínculos entre la ciencia, la naturaleza y la sociedad, así como mostrar las articulaciones de la Ciencia de la Sostenibilidad con la política científica, la educación universitaria y la salud pública. In this paper, the theory and the approaches of the science of sustainability (...) is promoted. Special emphasis is put on the academic Cuban context, when relating its emergence to the urgencies that appear within the links among science, nature and society. The interconnections of the science of sustainability with the scientific policy, the university education and the public health is shown as well as. (shrink)

Dejó dicho Jean Cocteau que su pesimismo no era sino una variedad de su optimismo. Se acordaba uno de este aforismo mientras atendía a las intervenciones de Javier Gomá y Alain Finkielkraut en el Institut Français de Madrid.1 Acaso el optimismo del español llegaba a desazonar un tanto más que el pesimismo del francés. Las diatribas de Finkielkraut, defensor acérrimo de la educación republicana francesa, dirigidas al periodo que abarca las últimas cuatro décadas, encontraban en Gomá, apólogo de la ejemplaridad2 (...) como método pedagógico y del cosmopolitismo ilustrado —“Ser español es la manera más práctica de ser contemporáneo”, subrayó aquel día—, respuesta en forma de pregunta: “¿En qué otra época preferirías vivir?”. Pregunta que resulta ciertamente tramposa cuando de lo que se trata es de analizar la deriva de las democracias liberales de un tiempo a esta parte, considerando a lo que se tendía ayer y pensando donde, en efecto, estamos hoy... (shrink)

El resentimiento es un fenómeno emocional complejo que afecta a la estructura existencial de la persona que lo sufre: a su modo de percibir, de relacionarse con otros y de encontrarse a sí misma en un mundo compartido. Desde la psicopatología se entiende como un rasgo desadaptativo de ciertos trastornos de la personalidad, y desde la teoría moral como una reacción negativa ante valores positivos y vitales —según el punto de vista parcial de Nietzsche, que minusvalora la vivencia de daño (...) y sufrimiento que está en su origen. Un acercamiento fenomenológico a la vida emocional resentida, de la mano de la fenomenología de Max Scheler y del relato en primera persona de Jean Améry, descubre el resentimiento como metamorfosis de la existencia personal, que puede adquirir un sentido trágico. Esta interpretación del fenómeno responde a la quiebra de la esencia de la simpatía, como forma de relación interpersonal básica, y a su reconstrucción como sentido básico de la justicia. (shrink)

Alejandro Tomasini ha indicado, muy lúcidamente, la necesidad de pensar los problemas filosóficos en lengua castellana. Más aún, ha sugerido que es posible tratar los problemas propios de la filosofía analítica por medio de la lengua castellana y que, por otra parte, es necesario en nuestro continente pensar los problemas y enfrentarlos analíticamente. Independientemente de su alcance teórico, el mérito del libro que presentamos, Lecturas analíticas: una introducción a temas y problemas de la filosofía analítica, apunta a esa dirección.

En el debate ético contemporáneo coexisten planteamientos derivados de la filosofía moral moderna con otros enfoques que cuestionan sus ambiciones normativas. Estos enfoques se han descrito como “éticas sin moral”, dando por sentado que el término “moral” recoge un aspecto nuclear del pensamiento ético moderno: el deseo de identificar las normas universales objetivas. En este ensayo me propongo examinar si es posible defender la normatividad de la razón sustrayéndose a las críticas esgrimidas desde las contemporáneas éticas sin moral.

En esta nota crítica (i) se hace una breve descripción de cada uno de los artículos que componen Orayen: de la forma lógica al significado, (ii) se señalan algunas cuestiones que no están claras en ellos o en las réplicas de Orayen y, (iii) en la medida de lo posible, se indica si los autores desarrollan ulteriormente los problemas abordados en sus artículos. The aim of this critical note is threefold: (i) it briefly describes and comments on each of the (...) articles of Orayen: de la forma lógica al significado; (ii) identifies some issues that may not be clear enough or not fully developed whether in the articles or even in Orayen's replies; (iii) as far as possible, it refers to further studies made by the authors themselves on the same, or quite related, subjects addressed by them in their papers. (shrink)

Socrates can be said to have left the subsequent philosophical tradition with the problem of the relation between philosophy and politics. Already in the Republic the proposal of philosopher-kings represents more a tension than an identity. While Aristotle responds by insisting on a sharp distinction between politics and philosophical wisdom, this distinction proves on closer examination much less sharp than might appear. Heidegger characterizes philosophy as the only authentic politics and the philosopher as ruling just by virtue of being a (...) philosopher. In contrast, Foucault insists that, if philosophy can play a role in relation to politics by transforming the subject who lives politically, it plays no role within politics. In this contrast can be seen the 'fallout' of the tension bequeathed by Socrates through both Plato and Aristotle. Podría decirse que Sócrates le dejó a la tradición filosófica posterior el problema de la relación entre filosofía y política. Ya en la República la propuesta del rey filósofo representa más una tensión que una identidad. Mientras que la respuesta de Aristóteles insiste en una clara distinción entre la política y la sabiduría filosófica, un examen cuidadoso demuestra que esta distinción es menos clara de lo que parece. Heidegger caracteriza la filosofía como la única política auténtica y al filósofo como gobernante por el mero hecho de ser filósofo. En contraste, Foucault insiste en que si bien la filosofía puede desempeñar un papel en relación con la política al transformar al sujeto que vive políticamente, aquella no desempeña papel alguno dentro de la política. Este contraste ilustra el resultado de la tensión legada por Sócrates a través de Platón y Aristóteles. (shrink)

La crítica horkheimeriana a la Ilustración muestra el proceso mediante el cual se desencadena la desmitificación del mundo por vía de un "acto de dominio" de la razón. Allí, el hombre perdió para la razón su posibilidad de autocrítica, haciendo que esta deviniera en razón instrumental. Desde sus comienzos, la Ilustración, en calidad de mito, mutiló la razón y, por encima de la búsqueda de la verdad -verdad teórica y verdad moral-, aconteció una "renuncia al sentido" donde el sueño de (...) la racionalidad ilustrada quedó reducido a la "instrumentalización". Esta dialéctica no solo devela la crisis irreversible de la razón, sino que deja vigente, en la discusión de la teoría crítica, la idea de una "patología social de la razón", a partir de la cual puede proponerse la reivindicación de un "horizonte normativo"; dejando entrever en el escenario de la discusión ética la falta de racionalidad de las sociedades. Horkheimerian's critique of the Enlightenment, shows the process whereby the demystification of the world is triggered by way of an "an act of sovereignty" of reason. There the man lost for reason his possibility of self-criticism, causing it to be in instrumental reason. Since its inception, the Enlightenment, as myth, mutilated reason, over the pursuit of truth -theoretical truth and moral truth-, there was a renounce to sense. The dream of Enlightenment rationality was reduced to the 'instrumentalization'. This dialectic not only reveals the irreversible crisis of reason, but leaves in place, in the discussion of critical theory, the idea of the 'social pathology of reason', from which a "normative horizon" can be proposed, hinting at the scene of the ethical discussion the lack of rationality of societies. (shrink)

Background: Chronic Pain (CP) has serious medical and social consequences, and leads to economic burden that threatens the sustainability of healthcare services. Thus, optimized management of pain tools to support CP patients in adjusting to their condition and improving quality of life is timely. Although Acceptance and Commitment Therapy (ACT) is considered an evidence-based psychological approach for CP, evidence for the efficacy of online-delivered ACT for CP is still scarce. At the same time, studies suggest that self-compassion mediates the change (...) in disability and psychopathological symptoms in ACT interventions for CP, although self-compassion is not a specific target in ACT. Thus, an explicit focus on self-compassion might increase the efficacy of ACT interventions for CP, although this hypothesis has not been tested. This study aims to develop an eHealth ACT and compassion-based self-management intervention for CP, the iACTwithPain, and to compare its efficacy in improving health outcomes to a similar ACT-only intervention and a waiting list group. Methods: The eHealth platform that will host the interventions will be developed using a flat design identity and will be interactive. The iACTwithPain intervention will comprise 8 weekly self-management sessions, and will be developed taking into consideration the psychological flexibility model applied to CP, with the addition of explicit compassion-based components. To analyse whether the iACTwithPain intervention will present superiority in improving CP’s impact and related health markers over the two other conditions, this study will follow a RCT design with three arms. CP patients will be recruited through direct contact with patient associations and healthcare services and a national press release in Portugal. Outcome measurement will be conducted at baseline, post-intervention and at 3- and 6-months follow-ups. The interventions’ acceptability will also be assessed. Discussion: The iACTwithPain intervention is expected to improve CP patients’ psychosocial functioning, quality of life, and empowerment, by promoting adaptive disease management and regulation of pain-related internal experiences. Results will contribute to a better understanding on the pertinence of adding compassion elements to ACT for CP and to reach an optimized intervention for CP. (shrink)

The IKt-algebras that we investigate in this paper were introduced in the paper An algebraic axiomatization of the Ewald’s intuitionistic tense logic by the first and third author. Now we characterize by topological methods the subdirectly irreducible IKt-algebras and particularly the simple IKt-algebras. Finally, we consider the particular cases of finite IKt-algebras and complete IKt-algebras.

En este artículo se examinan las referencias a Escoto de la obra poliana, y se discute en especial el voluntarismo escotísta que reduce el horizonte humano a su actividad esencial.

Ever since the publication of Halliday and Hasan, cohesion analysis has received much attention in several branches of linguistics. Lexical cohesion in particular has been shown to contribute to the coherence of discourse in a number of ways, and specific patterns of lexical cohesion have emerged as relevant for the description of different registers and genres. In the present article I challenge existing models of lexical cohesion and offer a revised one which affords particular attention to what I call ‘associative (...) cohesion’. I go on to test the adequacy of the proposed framework in a corpus of 15 telephone conversations extracted from the International Corpus of English-Great Britain. Using both quantitative and qualitative methods the article analyses 3480 ties and demonstrates that telephone conversations are lexically cohesive mostly due to repetitions, associative cohesion and inclusive relations, which overwhelmingly occur across the turns and over remote-mediated spans. In addition, lexical patterns are shown to collaborate in topic management processes and to be sensitive to genre-specific factors, thereby demonstrating the descriptive potential and applicability of the framework. (shrink)